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Academic Journal

Ketoheterocycle-based inhibitors of cathepsin K: A novel entry into the synthesis of peptidic ketoheterocycles

Authors : Tavares, Francis X.; Deaton, David N.; Miller, Aaron B.

Source: Bioorganic & Medicinal Chemistry Letters. Sept 1, 2005, Vol. 15 Issue 17, p3891, 5 p.

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Academic Journal

Oxidation of oxazolines and thiazolines to oxazoles and thiazoles. Application of the Kharasch-Sosnovsky reaction

Authors : Meyers, A.I.; Tavares, Francis X.

Source: Journal of Organic Chemistry. Nov 15, 1996, Vol. 61 Issue 23, p8207, 9 p. table

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Academic Journal

Ketoheterocycle-Based Inhibitors of Cathepsin K: A Novel Entry into the Synthesis of Peptidic Ketoheterocycles.

Authors : Tavares, Francis X.; Deaton, David N.; Miller, Aaron B.

Source: ChemInform; Dec2005, Vol. 36 Issue 51, pno-no, 1p

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Academic Journal

Novel and Potent Cyclic Cyanamide-Based Cathepsin K Inhibitors.

Authors : Deaton, David N.; Hassell, Anne M.; McFadyen, Robert B.

Source: ChemInform; Jul2005, Vol. 36 Issue 30, pno-no, 1p

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Academic Journal

Orally Bioavailable Small Molecule Ketoamide-Based Inhibitors of Cathepsin K.

Authors : Barrett, David G.; Catalano, John G.; Deaton, David N.

Source: ChemInform; Sep2004, Vol. 35 Issue 39, pno-no, 1p

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Academic Journal

Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy

Authors : Thomson, Stephen A. ; Banker, Pierette¹; Bickett, D. Mark¹

Source: Bioorganic & Medicinal Chemistry Letters. Feb2009, Vol. 19 Issue 4, p1177-1182. 6p.

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Academic Journal

Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of Type 2 diabetes: 2. Optimization of serine and threonine ether amino acid residues

Authors : Sparks, Steven M. ; Banker, Pierette¹; Bickett, David M.¹

Source: Bioorganic & Medicinal Chemistry Letters. Feb2009, Vol. 19 Issue 3, p981-985. 5p.

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Academic Journal

Anthranilimide-based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes: 1. Identification of 1-amino-1-cycloalkyl carboxylic acid headgroups

Authors : Sparks, Steven M. ; Banker, Pierette¹; Bickett, David M.¹

Source: Bioorganic & Medicinal Chemistry Letters. Feb2009, Vol. 19 Issue 3, p976-980. 5p.

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Academic Journal

Acyclic, orally bioavailable ketone-based cathepsin K inhibitors

Authors : Barrett, David G.¹; Catalano, John G.¹; Deaton, David N.¹

Source: Bioorganic & Medicinal Chemistry Letters. Jan2007, Vol. 17 Issue 1, p22-27. 6p.

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Academic Journal

The discovery and optimization of pyrimidinone-containing MCH R1 antagonists

Authors : Hertzog, Donald L. ; Al-Barazanji, Kamal A.¹; Bigham, Eric C.¹

Source: Bioorganic & Medicinal Chemistry Letters. Sep2006, Vol. 16 Issue 18, p4723-4727. 5p.

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