Search Results

Combined noncanonical NF-[kappa]B agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo

• Authors : Falcinelli, Shane D.; Peterson, Jackson J.; Turner, Anne-Marie W.

• Source: Journal of Clinical Investigation. April 15, 2022, Vol. 132 Issue 8

Record details

Improved methods for targeting epigenetic reader domains of acetylated and methylated lysine

• Authors : Engelberg, Isabelle A.; Foley, Caroline A.; James, Lindsey I.

• Source: Current Opinion in Chemical Biology. August 2021, Vol. 63, 132

Record details

Bioorthogonal Chemical Epigenetic Modifiers Enable Dose-Dependent CRISPR Targeted Gene Activation in Mammalian Cells.

• Authors : Dongbo Lu; Foley, Caroline A.; Birla, Shama V.

• Source: ACS Synthetic Biology; 4/15/2022, Vol. 11 Issue 4, p1397-1407, 11p

Record details

Cdyl Deficiency Brakes Neuronal Excitability and Nociception through Promoting Kcnb1 Transcription in Peripheral Sensory Neurons.

• Authors : Sun, Zhao‐Wei; Waybright, Jarod M.; Beldar, Serap

Subjects: DORSAL root ganglia; SENSORY neurons; POTASSIUM channels

• Source: Advanced Science; Apr2022, Vol. 9 Issue 10, p1-22, 22p

Record details

Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding.

• Authors : Kean, Kelsey M.; Baril, Stefanie A.; Lamb, Kelsey N.

• Source: Journal of Medicinal Chemistry; 2/10/2022, Vol. 65 Issue 3, p2646-2655, 10p

Record details

Discovery of Potent Peptidomimetic Antagonists for Heterochromatin Protein 1 Family Proteins.

• Authors : Lamb, Kelsey N.; Dishman, Sarah N.; Waybright, Jarod M.

• Source: ACS Omega; 1/11/2022, Vol. 7 Issue 1, p716-732, 17p

Record details

Peptide Technologies in the Development of Chemical Tools for Chromatin-Associated Machinery

• Authors : Gurwitz, David; Barnash, Kimberly D.; Lamb, Kelsey N.

• Source: Drug Development Research. Sept, 2017, Vol. 78 Issue 6, p300, 13 p.

Record details

Design, synthesis, and protein methyltransferase activity of a unique set of constrained amine containing compounds

• Authors : Zhou, Hao; Che, Xin; Bao, Guochen

• Source: Bioorganic & Medicinal Chemistry Letters. Sept 15, 2016, Vol. 26 Issue 18, p4436, 5 p.

Record details

Chemical probes for methyl lysine reader domains

• Authors : James, Lindsey I.; Frye, Stephen V.

• Source: Current Opinion in Chemical Biology. August, 2016, Vol. 33, p135, 7 p.

Record details

Getting a handle on chemical probes of chomatin readers.

• Authors : Waybright, Jarod M; James, Lindsey I

• Source: Future Medicinal Chemistry; Apr2021, Vol. 13 Issue 8, p749-763, 15p

Record details

Chromatin remodeling controls Kaposi's sarcoma-associated herpesvirus reactivation from latency

• Authors : Hopcraft, Sharon E.; Pattenden, Samantha G.; James, Lindsey I.

• Source: PLoS Pathogens. Sept 13, 2018, Vol. 14 Issue 9, pe1007267.

Record details

Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2.

• Authors : Ferreira de Freitas, Renato; Liu, Yanli; Szewczyk, Magdalena M.

• Source: Journal of Medicinal Chemistry; 2/11/2021, Vol. 64 Issue 3, p1584-1592, 9p

Record details

Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors.

• Authors : Jefferys, Stuart R.; Burgos, Samuel D.; Peterson, Jackson J.

Subjects: HIV infections; TRANSCRIPTION factors; FORKHEAD transcription factors

• Source: PLoS Pathogens; 2/26/2021, Vol. 17 Issue 2, p1-31, 31p

Record details

Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1

• Authors : Suh, Junghyun L.; Watts, Brian; Stuckey, Jacob I.

• Source: Biochemistry. April 10, 2018, Vol. 57 Issue 14, 2140-2149

Record details

Modulation of p38 MAPK signaling enhances dendritic cell activation of human CD4.sup.+ Th17 responses to ovarian tumor antigen

• Authors : Cannon, Martin J.; Goyne, Hannah E.; Stone, Pamela J. B.

• Source: Cancer Immunology, Immunotherapy. May 2013, Vol. 62 Issue 5, p839, 11 p.

Record details

A case of acquired dysfibrinogenemia in multiple myeloma treated with therapeutic plasma exchange

• Authors : Post, Ginell R.; James, Lindsey; Alapat, Daisy

• Source: Transfusion and Apheresis Science. Feb 2013, Vol. 48 Issue 1, p35, 4 p.

Record details

Assessing the Cell Permeability of Bivalent Chemical Degraders Using the Chloroalkane Penetration Assay.

• Authors : Foley, Caroline A.; Potjewyd, Frances; Lamb, Kelsey N.

• Source: ACS Chemical Biology; Jan2020, Vol. 15 Issue 1, p290-295, 6p

Record details

Targeting Regorafenib-Induced Toxicity through Inhibition of Gut Microbial β‑Glucuronidases.

• Authors : Ervin, Samantha M.; Hanley, Ronan P.; Lim, Lauren

• Source: ACS Chemical Biology; Dec2019, Vol. 14 Issue 12, p2737-2744, 8p

Record details

Junior college, a successful experiment.

• Authors : Robb, James Lindsey

• Source: Southern Association Quarterly; May 1941, Vol. 5, p283-287, 5p

Record details

Social adventures of the junior college.

• Authors : Robb, James Lindsey

• Source: Junior College Journal; May 1936, Vol. 6, p454-460, 7p

Record details

Guidance in the junior college.

• Authors : Robb, James Lindsey

• Source: Junior College Journal; May 1932, Vol. 2, p427-434, 8p

Record details

Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.

• Authors : James, Lindsey I¹; Barsyte-Lovejoy, Dalia²; Zhong, Nan²

• Source: Nature Chemical Biology. Mar2013, Vol. 9 Issue 3, p184-191. 8p. 1 Color Photograph, 3 Diagrams, 2 Graphs.

Record details

A synthetic receptor for asymmetric dimethyl arginine

• Authors : James, Lindsey I.; Beaver, Joshua E.; Rice, Natalie W.

• Source: Journal of the American Chemical Society. May 1, 2013, Vol. 135 Issue 17, 6450-6455

Record details

Structure-activity relationships and cellular mechanism of action of small molecules that enhance the delivery of oligonucleotides.

• Authors : Juliano, Rudolph L; Wang, Ling; Tavares, Francis

• Source: Nucleic Acids Research; 2/28/2018, Vol. 46 Issue 4, p1601-1613, 13p

Record details

Peptide Technologies in the Development of Chemical Tools for Chromatin-Associated Machinery.

• Authors : Barnash, Kimberly D.; Lamb, Kelsey N.; James, Lindsey I.

Subjects: CHROMATIN; POST-translational modification; PEPTIDES

• Source: Drug Development Research; Sep2017, Vol. 78 Issue 6, p300-312, 13p

Record details

Gut Microbial β-Glucuronidase Inhibition via Catalytic Cycle Interception

• Authors : Pellock, Samuel J.; Creekmore, Benjamin C.; Walton, William G.

• Source: ACS Central Science; July 2018, Vol. 4 Issue: 7 p868-879, 12p

Record details

Target class drug discovery

• Authors : Barnash, Kimberly D; James, Lindsey I; Frye, Stephen V

• Source: Nature Chemical Biology; October 2017, Vol. 13 Issue: 10 p1053-1056, 4p

Record details

Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2.

• Authors : Barnash, Kimberly D.; The, Juliana; Norris-Drouin, Jacqueline L.

• Source: ACS Combinatorial Science; 3/13/2017, Vol. 19 Issue 3, p161-172, 12p

Record details

Structure-Activity Relationships and Kinetic Studies of Peptidic Antagonists of CBX Chromodomains.

• Authors : Stuckey, Jacob I.; Simpson, Catherine; Norris-Drouin, Jacqueline L.

• Source: Journal of Medicinal Chemistry; Oct2016, Vol. 59 Issue 19, p8913-8923, 11p

Record details

Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.

• Authors : Falcinelli, Shane D.; Peterson, Jackson J.; Turner, Anne-Marie W.

• Source: Journal of Clinical Investigation. 4/15/2022, Vol. 132 Issue 8, p1-14. 14p.

Record details

Small-Molecule Modulation of Methyl-Lysine-Mediated Interactions.

• Authors : Frye, Stephen V.; James, Lindsey I.

• Source: Histone Recognition; 2015, p243-271, 29p

Record details

Chromodomain Ligand Optimization via Target-Class Directed Combinatorial Repurposing

• Authors : Barnash, Kimberly D.; Lamb, Kelsey N.; Stuckey, Jacob I.

• Source: ACS Chemical Biology; September 2016, Vol. 11 Issue: 9 p2475-2483, 9p

Record details

Contributions of pocket depth and electrostatic interactions to affinity and selectivity of receptors for methylated lysine in water.

• Authors : E. Beaver, Joshua; C. Peacor, Brendan; V. Bain, Julianne

• Source: Organic & Biomolecular Chemistry; 2015, Vol. 13 Issue 11, p3220-3226, 7p

Record details

The L3MBTL3 Methyl-Lysine Reader Domain Functions As a Dimer

• Authors : Baughman, Brandi M.; Pattenden, Samantha G.; Norris, Jacqueline L.

• Source: ACS Chemical Biology; March 2016, Vol. 11 Issue: 3 p722-728, 7p

Record details

A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1

• Authors : Stuckey, Jacob I; Dickson, Bradley M; Cheng, Nancy

• Source: Nature Chemical Biology; February 2016, Vol. 12 Issue: 3 p180-187, 8p

Record details

Madison Ave Media, Inc. (NBB: KHZM)

Record details

Small-MoleculeLigands of Methyl-Lysine Binding Proteins:Optimization of Selectivity for L3MBTL3.

• Authors : James, Lindsey I.; Korboukh, Victoria K.; Krichevsky, Liubov

• Source: Journal of Medicinal Chemistry; Vol. 56 Issue 18, p7358-7371, 14p

Record details

The structure–activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface.

• Authors : Camerino, Michelle A.; Zhong, Nan; Dong, Aiping

• Source: MedChemComm; 2013, Vol. 4 Issue 11, p1501-1507, 7p

Record details

Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1

• Authors : Perfetti, Michael T.; Baughman, Brandi M.; Dickson, Bradley M.

• Source: ACS Chemical Biology; April 2015, Vol. 10 Issue: 4 p1072-1081, 10p

Record details

Tennessee Wesleyan college.

• Authors : Robb, James Lindsey

• Source: Southern Association Quarterly; November 1940, Vol. 4, p584-585, 2p

Record details

An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

• Authors : Konze, Kyle D.; Ma, Anqi; Li, Fengling

• Source: ACS Chemical Biology; June 2013, Vol. 8 Issue: 6 p1324-1334, 11p

Record details

Conflict of Laws, or Private International Law Raleigh C. Minor

• Authors : Heard, James Lindsey; Richey, Homer; Nelson, Roscoe C.

• Source: The Virginia Law Register. 7(6):452-454

Record details

Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing.

• Authors : Moussa, Hagar F.; Bsteh, Daniel; Yelagandula, Ramesh

• Source: Nature Communications; 4/29/2019, Vol. 10 Issue 1, pN.PAG-N.PAG, 1p

Record details

Correction to "Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID subunit 1".

• Authors : Suh, Junghyun L.; Watts, Brian; Stuckey, Jacob I.

• Source: Biochemistry; 12/11/2018, Vol. 57 Issue 49, p6806-6806, 1p

Record details

A Novel Family of Small Molecules that Enhance the Intracellular Delivery and Pharmacological Effectiveness of Antisense and Splice Switching Oligonucleotides

• Authors : Wang, Ling; Ariyarathna, Yamuna; Ming, Xin

• Source: ACS Chemical Biology; 20180101, Issue: Preprints

Record details

Retraction of “The L3MBTL3 Methyl-Lysine Reader Domain Functions As a Dimer”

• Authors : Baughman, Brandi M.; Pattenden, Samantha G.; Norris, Jacqueline L.

• Source: ACS Chemical Biology; November 2017, Vol. 13 Issue: 1 p281-281, 1p

Record details

APA PsycInfo

Record details

Structural Basis for the Binding Selectivity of Human CDY Chromodomains.

• Authors : Dong, Cheng¹ (AUTHOR); Liu, Yanli^1,2,3 (AUTHOR); Lyu, Tian-Jie^1,4 (AUTHOR)

• Source: Cell Chemical Biology. Jul2020, Vol. 27 Issue 7, p827-827. 1p.

Record details

Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader.

• Authors : Potjewyd, Frances¹ (AUTHOR); Turner, Anne-Marie W.² (AUTHOR); Beri, Joshua³ (AUTHOR)

• Source: Cell Chemical Biology. Jan2020, Vol. 27 Issue 1, p47-47. 1p.

Record details

Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7.

• Authors : Lamb, Kelsey N.¹ (AUTHOR); Bsteh, Daniel^2,3 (AUTHOR); Dishman, Sarah N.¹ (AUTHOR)

• Source: Cell Chemical Biology. Oct2019, Vol. 26 Issue 10, p1365-1365. 1p.

Record details